This systematic review identifies types of child sexual abuse (CSA) prevention initiatives being implemented in developing countries and their effectiveness. Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, the authors searched six databases and identified eight peer-reviewed published studies to analyse; all the studies reviewed used quasi-experimental or experimental designs. Most empirically evaluated interventions in developing countries have focused on preschool and primary school-aged children, and the Body Safety Training programme was the most used intervention in the review. Most have focused on interventions delivered in educational settings, with a lack of focus on large-scale government-led interventions. Those who are out of school, which disproportionately are girls from low socio-economic backgrounds, are often unable to access current interventions. Furthermore, there is a lack of comparative analysis of two or more programmes. Researchers have used outcomes measuring knowledge or skills for young people in self-protection and help-seeking, noting statistically significant increases in abuse prevention knowledge. However, deployment of those skills was not measured, and there is a lack of evidence that awareness leads to an actual reduction in prevalence of CSA and/or improvements in conditions of safety in organisational contexts.